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George
W. Irving, III, DVM, MS
Vice President, S&T Support Services
Research
Contributions:
Performed independent research on the ingestive capacity of peritoneal
macrophages in mice exposed to hypobaric and hypoxic environment.
This work was performed in altitude chambers at the USAF School
of Aerospace Medicine, Brooks AFB, TX.
Performed independent
research in the spontaneous diseases of laboratory animals. This
research involved epidemiologic investigation and studies of disease
pathogenesis in rodents, rabbits, and primates housed in the Animal
Colony of the Armed Forces Institute of Pathology (AFIP).
Collaborated
with Drs. N. Rao and J. D. Wright, on research in demyelinating
diseases of man using various animal models. These included the
guinea pig and the nonhuman primate. The research focused on the
study of experimental allergic optic neuritis, its association with
demyelinating diseases, such as multiple sclerosis, its pathogenesis,
and techniques for its diagnosis.
Collaborated
with Drs. N. Rao and D. Ochs, on surgical research and developed
a technique for surgical exposure of the optic nerve in the guinea
pig for use in studies of experimental allergic optic neuritis.
Collaborated
with members of the Forensic Pathology Division of the Armed Forces
Institute of Pathology on studies of shored exit gunshot wounds
using the domestic pig as the animal model.
Performed research
in the genetics of a hairless condition in the laboratory rat with
Dr. F. G. Ferguson (Pennsylvania State University). This study consisted
of the characterization of the histologic and gross appearance of
the mutation and genetic crosses to identify the chromosomal location
of the mutant gene.
Collaborated
with Dr. D. Connors of the AFIP, on studies of the etiology of the
condition "Myospherulosis," a clinical entity found in various areas
of Africa. The model used was the rat.
Worked with investigators
from the Walter Reed Army Institute of Research and the National
Institutes of Health on the development of the Mystromys albicaudatus
(African White Tailed Rat) as an animal model for schistosomiasis.
Collaborated
with Drs. Myers, Binford, and Walsh on the development of the armadillo
as an animal model for Leprosy. Assisted in the study of various
aspects of the development of a Leprosy vaccine using these animals
in a WHO-supported research center at the AFIP.
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